butabarbital will minimize the level or result of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.butabarbital will lessen the level or effect of cyclosporine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.near Be sure to ensure that you want to to Sign off of Medscape